Ученые из НУС и Duke-NUS получили гранты на изучение рисков зоонозных заболеваний в Сингапуре

Five projects led by NUS and Duke-NUS Medical School will study zoonotic disease risks linked to urban birds, ticks, wildlife mammals, domestic dogs and cats, and wild and domestic birds as part of a national effort to improve early detection and prevention of potential outbreaks, with the aim of strengthening the country's long-term public health resilience. These projects are among six research efforts awarded grants by the National Parks Board (NParks) under the Biosurveillance Research Programme, a S$15 million initiative under Singapore's Research, Innovation and Enterprise 2025 Plan. Developed in partnership with agencies under Singapore's One Health framework which recognises that human, animal and environmental health are closely connected, the programme brings together multidisciplinary research teams to advance understanding of zoonotic diseases and their drivers in Singapore, and develop evidence-based strategies for mitigating future disease risks. The projects led by NUS and Duke-NUS focus on understanding how diseases move between wildlife and domestic animals, the environment and people in Singapore's urban landscape. Tracking disease risks from urban birds Professor Karina Gin from the Department of Civil and Environmental Engineering at the College of Design and Engineering will lead a project on pathogen risks from urban birds, including pigeons and crows. The team will use environmental sampling and modelling to understand what pathogens these birds may carry, and how these could reach human populations. Prof Gin said, "In densely populated environments like Singapore, we share our space with a surprising amount of wildlife. While this can be a positive aspect of urban living, it also public health considerations worth examining." "This study is vital because it moves beyond simply acknowledging the presence of urban birds to actively identifying the specific pathogens they carry and how those pathogens might reach the human population. Our work supports the 'One Health' approach, which is relevant to understand the public health dynamics of a dense urban environment," she added. Mapping tick-borne pathogens across Singapore In another project, Associate Professor Benoit Malleret from the Department of Microbiology and Immunology at the Yong Loo Lin School of Medicine will lead a team to create a Singapore Integrated Network for Genomic and Epidemiological Tick-borne Pathogen Investigation and Connectivity (SINGETIC). The project studies ticks found across Singapore and the diseases they may spread from animals to people. The team will use modern laboratory testing to create mapping and forecasting tools to identify possible risk areas, highlight spillover hotspots and explain how infections spread. "Ticks are part of Singapore's natural environment, and understanding what they carry is essential for protecting both people and animals. As a 'One Health' effort, we are combining field sampling with advanced lab testing to strengthen early detection of tick-borne pathogens. ," said Assoc Prof Malleret. Understanding disease transmission in wildlife Associate Professor Kimberly Fornace from the Saw Swee Hock School of Public Health will lead a project integrating spatial, ecological and biological data to improve surveillance for zoonotic pathogens in mammalian wildlife. The study will focus on understanding and predicting potential disease transmission from wildlife, such as macaques and bats, to humans. "Understanding diseases in wildlife is essential for maintaining healthy ecosystems and safeguarding human and animal populations. By monitoring wildlife health, we can better understand and respond to infectious diseases and protect biodiversity in our shared environments," said Assoc Prof Fornace. Companion animals and zoonotic disease A team led by Professor Gavin Smith from Duke-NUS Medical School will examine the risk of zoonotic disease transmission between domestic cats and dogs and humans. The team will study a range of settings, including veterinary clinics and pet establishments, to better understand how pathogens may spread between animals and people and identify ways to reduce spillover risks. "Diseases that can spread between pets and people are an ongoing area of research," said Prof Smith. "This study will examine how key infections spread among cats and dogs, and whether they can be passed to their owners and caretakers. The findings will support stronger disease monitoring and help guide public health measures to better manage potential zoonoses in pets in urban communities." Bird flu surveillance A project led by Assistant Professor Yvonne Su from Duke-NUS Medical School will assess the risk of avian influenza A viruses in Singapore's wild and domestic bird populations. By combining studies of bird flu viruses with data on bird ecology and movement, the team aims to better understand how these viruses circulate and spread, supporting future surveillance and preparedness efforts. Assoc Prof Su said, "Avian influenza is a growing global health and biosecurity concern, particularly as H5N1 viruses continue to spread across continents and infect an expanding range of animal species. As a key stopover for migratory birds, Singapore plays an important role in monitoring these evolving risks." Turning to the study's approach, she said, "This pioneering study in Singapore will utilise advanced phylodynamic and modelling approaches to track virus strains, providing critical insights into how avian influenza viruses may be introduced and circulate within local wild bird populations. The findings will strengthen Singapore's capacity for early detection, surveillance and rapid response to emerging zoonotic threats." By studying how pathogens move through urban ecosystems, the research teams aim to strengthen Singapore's ability to detect emerging risks early and develop evidence-based strategies to protect public health.