Новая технология на основе РНК значительно повышает выживаемость клеток поджелудочной железы при трансплантации

Just read this story at Forbes, which I caught from my Bluesky feed, here: Forbes story, from the link on Bluesky I was able to read through, without a paywall, so please try to open the link via the embed I’ve dropped just above this text. If that won’t work for you, here’s the URL of the story at Forbes: The gist of the News: Type 1 diabetes affects millions, and islet cell transplantation offers a promising treatment by restoring insulin-producing beta cells. However, most transplanted cells die shortly after surgery due to insufficient revascularization. A new RNA technology addresses this by using a targeting aptamer and a gene-activating RNA (saRNA). This combination transiently boosts VEGF-A production in beta cells, promoting the necessary blood supply. This innovative approach significantly increases beta cell survival post-transplantation in animal models. Expected human clinical trials could revolutionize diabetes treatment and other cell-based therapies. As a 15 year diagnosed Type II Diabetic, this news is truly astonishing. In a decade or so, most people, even Type 1 Diabetics, might be free from injecting insulin and possibly even oral medications like Metformin (a biguanides class drug). I fully expect to read a story somewhere that the current Secretary of Health and Human Services, Brain Worm Guy, has said this news is bullshit and diabetics just need to … do something icky and/or stupid, instead of following their MEDICAL DOCTOR’s advice.